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Test Code OPATU Opiates Confirmation, Random, Urine

Important Note

Reflex Only

Additional Codes

Outreach (Atlas) Order Code                       

OPIUCONF

Hospital (Cerner) Order Code 

OPATU

Reporting Name

Opiate Confirmation, U

Useful For

Detection and quantification of codeine, hydrocodone, oxycodone, morphine, hydromorphone, oxymorphone, noroxycodone, noroxymorphone, norhydrocodone, dihydrocodeine, and naloxone in urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order OPATX / Opiates Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available; call 800-533-1710.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

2.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reference Values

Negative

 

Cutoff concentrations by liquid chromatography tandem mass spectroscopy:

Codeine: 25 ng/mL

Dihydrocodeine: 25 ng/mL

Hydrocodone: 25 ng/mL

Norhydrocodone: 25 ng/mL

Hydromorphone: 25 ng/mL

Oxycodone: 25 ng/mL

Noroxycodone: 25 ng/mL

Oxymorphone: 25 ng/mL

Noroxymorphone: 25 ng/mL

Naloxone: 25 ng/mL

Morphine: 25 ng/mL

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80361

80365

80362

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPATU Opiate Confirmation, U In Process

 

Result ID Test Result Name Result LOINC Value
6543 Codeine-by LC-MS/MS 16250-3
42000 Dihydrocodeine-by LC-MS/MS 19448-0
21177 Hydrocodone-by LC-MS/MS 16252-9
42001 Norhydrocodone-by LC-MS/MS 61422-2
21179 Hydromorphone-by LC-MS/MS 16998-7
21178 Oxycodone-by LC-MS/MS 16249-5
42002 Noroxycodone-by LC-MS/MS 61425-5
35023 Oxymorphone-by LC-MS/MS 17395-5
42003 Noroxymorphone-by LC-MS/MS 90894-7
42004 Naloxone-by LC-MS/MS 77207-9
6542 Morphine-by LC-MS/MS 16251-1
21180 Opiates Interpretation 69050-3

Report Available

3 to 5 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.

Secondary ID

8473