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HelpTest Code MPU Monoclonal Protein Studies, 24 Hour, Urine
Additional Codes
Outreach (Atlas) Order Code
MPSU
Hospital (Cerner) Order Code
MPU
Shipping Instructions
Refrigerate specimen during collection and send refrigerated.
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Supplies: Urine Container, 60 mL (T313)
Submission Container/Tube: Plastic, 60-mL urine bottle
Specimen Volume: 50 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Aliquot between 30 mL and 50 mL urine into plastic, 60-mL urine bottle.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Secondary ID
616911Useful For
Monitoring patients with monoclonal gammopathies
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| MPTU | M-protein Mass-Fix, 24 HR, U | No | Yes |
| PEU | Protein Electrophoresis, 24 Hr, U | No | Yes |
| PTU3 | Protein, Total, 24 HR, U | Yes, (Order PTU) | Yes |
Testing Algorithm
The following algorithms are available:
Special Instructions
Method Name
PTU: Turbidimetry
PEU: Agarose Gel Electrophoresis
MPTU: Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)
Reporting Name
M-protein Studies, 24 HR, USpecimen Type
UrineSpecimen Minimum Volume
30 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 5 days | ||
| Ambient | 24 hours |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Reference Values
PROTEIN, TOTAL:
<229 mg/24 hours
Reference values have not been established for patients <18 years of age.
ELECTROPHORESIS, PROTEIN:
The following fractions, if present, will be reported as mg/24 hours:
Albumin
Alpha-1 globulin
Alpha-2 globulin
Betaglobulin
Gamma globulin
MASS-FIX M-PROTEIN ISOTYPE:
M-protein Isotype MS:
No monoclonal protein detected
Flag M-protein Isotype MS:
Negative
Day(s) Performed
Monday through Friday
Report Available
4 to 6 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84156
84166
0077U
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MPU | M-protein Studies, 24 HR, U | 101910-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 607970 | Albumin | 6941-9 |
| 617117 | M-protein Isotype MS, 24 HR, U | In Process |
| TP6 | Total Protein, 24 HR, U | 2889-4 |
| TM24 | Collection Duration | 13362-9 |
| 617118 | Flag M-protein Isotype MS, 24 HR, U | No LOINC Needed |
| 607971 | Alpha-1 globulin | 6794-2 |
| 607972 | Alpha-2 globulin | 6795-9 |
| VL92 | Urine Volume | 3167-4 |
| 607973 | Beta globulin | 94714-3 |
| 607974 | Gamma globulin | 94715-0 |
| 2833 | A/G Ratio | 44294-7 |
| 21446 | M spike | 42482-0 |
| 22307 | M spike | 42482-0 |
| 21447 | Impression | 32210-7 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.
Monoclonal Protein Timed Urine
Immunofixation Urine Timed