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Test Code ANTI XA Anti Xa Heparin LMW

Cerner Test Code

AntiXa LMW

Acceptable Collection Tube(s) or Specimen

Blue

Specimen Draw Volume

Volume: 2.7 mL

Minimum Volume: 2.7 mL

Processing Instructions

Draw 2.7 ml in a Blue Top tube. Tube must be filled appropriately to the fill line to ensure accurate results. Centrifuge tube, aliquot 1.0 mL plasma, centrifuge plasma again, and place 1 ml of platelet-poor plasma in an aliquot tube and freeze.

Stability

Stability: Plasma: Room temp 4 hrs, Refrigerated 4 hrs ,Frozen 1 week, Whole Blood: tubes left capped/unspun are stable for 1 hour at room temperature.

Performed Test Frequency

Everyday

CPT(s)

85335

Methodology

Synthetic chromogenic substrate

Performing Location

MercyOne Des Moines Laboratory, Hematology

Clinical Significance

Low molecular weight heparins(LMWH) and unfractionated heparins(UFH) are used for the prevention and treatment of thromboembolic diseases. The quantitative determination of plasma LMWH/UFH levels is preferred/encouraged for monitoring treatment efficacy. UFH-pharmacy recommends drawing 6 hrs post heparin infusion or 6 hrs post dose adjustment. LMWH- pharmacy recommends the 1st level drawn 4 hrs post 3rd dose. Patients can be on LMWH Q12 or Q24 injections. Subsequent LMWH levels aren’t necessary unless there is a dose adjustment.

Reference Range

The therapeutic range is for LMWH is 0.5-1.0 IU/ml.