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Test Code ANCA Anti Neutrophil Cytoplasmic Ab Screen, P and C

Cerner Test Code

ANCA PC

Acceptable Collection Tube(s) or Specimen

Preferred: Gold SST

Acceptable: Red Top

Specimen Draw Volume

Volume: 2.0 mL

Minimum Volume: 1.0 mL

Processing Instructions

Draw in a Red top tube. Allow tube to clot for 30 minutes, centrifuge, aliquot and refrigerate.

Stability

Stability: Refrigerated 7 days, Frozen

Performed Test Frequency

Weekdays

CPT(s)

86255|TITER INCLUDED (86256) IF POSITIVE

Methodology

Indirect Immunofluorescence Assay (IFA)

Performing Location

MercyOne Des Moines Laboratory, Immunology

Rejection Criteria

Rejection criteria: Plasma, hemolysis or lipemia.

Clinical Significance

Evaluating patients suspected of having autoimmune vasculitis (both Wegener granulomatosis [WG] and microscopic polyangiitis). May be useful for monitoring treatment response in patients with WG (systemic or organ-limited disease); increasing titer suggests relapse of disease, while a decreasing titer suggests successful treatment.