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Test Code AMPHU Amphetamines Confirmation, Random, Urine

Important Note

Reflex Only

Additional Codes

Outreach (Atlas) Order Code                       

AMPHUC

Hospital (Cerner) Order Code 

AMPHU

Reporting Name

Amphetamines Confirmation, U

Useful For

Confirming drug exposure involving amphetamines such as amphetamine and methamphetamine, phentermine, pseudoephedrine/ephedrine, methylenedioxyamphetamine (MDA), and methylenedioxymethamphetamine (MDMA).

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order AMPHX / Amphetamines Confirmation, Chain of Custody, Random, Urine.

 

Additional drug panels and specific requests are available; call 800-533-1710.



Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 1 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise our ability to perform all necessary testing.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Negative

 

Cutoff concentrations by liquid chromatography tandem mass spectrometry:

Amphetamine: <25 ng/mL

Methamphetamine: <25 ng/mL

Phentermine: <25 ng/mL

Methylenedioxyamphetamine: <25 ng/mL

Methylenedioxymethamphetamine: <25 ng/mL

Pseudoephedrine/ephedrine: <25 ng/mL reported as negative

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80325

80359

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
AMPHU Amphetamines Confirmation, U 97161-4

 

Result ID Test Result Name Result LOINC Value
2934 Amphetamine-by LC-MS/MS 20410-7
29278 Phentermine-by LC-MS/MS 20557-5
2550 Methamphetamine-by LC-MS/MS 16235-4
29279 Pseudoephedrine/Ephedrine-by LC-MS/MS 58707-1
29280 MDA (Ecstasy metabolite)-by LC-MS/MS 20545-0
29281 MDMA (Ecstasy)-by LC-MS/MS 18358-2
21197 Amphetamines Interpretation 69050-3

Report Available

3 to 5 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Secondary ID

8257

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.